Studies in detoxication. 31. The isolation of m- and p-cyanophenols as metabolites of cyanobenzene (benzonitrile) and the problem of the orientation of hydroxyl groups formed in vivo.

We wish to express our thanks to Prof. J. M. Peterson and Dr John Pryde of University College, Cardiff, for the loan of the Perspex respiration tank used in this work. We are also grateful to Prof. Sir Alexander Fleming, F.R.S., for animal accommodation, and to Prof. A. St G. Huggett for the loan of a flowmeter. The expenses ofthis work were in part defrayed by a grant from the Medical Research Council.